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As a scientist and engineer, I strive to develop bioelectronic devices for health monitoring and enhancing the quality of life. Trained as a materials chemist, I have gained broad expertise in developing novel inorganic and organic materials with tunable physical and chemical properties to interface with biological systems, ranging from single cells to brain tissue, and from free-moving animals to human subjects. I am excited by the prospect of developing novel bioelectronics systems, such as implantable and wearable devices, and applying these systems in biomedicine and personal monitoring.

 

I have published 32 peer-reviewed papers, appearing in prestigious journals, including 12 first-author papers in Nature Electronics, Science Advances, Nature Reviews Bioengineering, ACS Nano, and Nano Letters. The goal of my research is to develop tools for studying the dynamic connections between different biomolecules and across various parts of the body, thereby elucidating the body's chemical connectome and facilitating a deeper understanding of metal disorders and chronic stress.

My research approach covers fundamental chemical biosensor development, materials and device engineering, and system integration to interface with different parts of the body. The core of my research is to understand the interactions between bioreceptors and biomolecules and develop transducers and post-processing units to process and amplify the signals from biomarkers. To interface with the body for wearable and implantable applications, device and material engineering are also critical for achieving a skin-like, tissue-like body-machine interface, enabling long-term and stable recordings with high signal fidelity.

Materials and device development

System integration and biomedical applications

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Research highlights

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Drift-free soft OFET biosensors with built-in differential circuits

Zhao#, Park# et al. Nat. Electron. (2025)

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A wearable biosensing system for sweat hormone monitoring

Wang#, Zhao# et al. Sci. Adv. (2022)

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Implantable aptamer–field-effect transistor neuroprobes for in vivo neurotransmitter monitoring

Zhao et al. Sci. Adv. (2021)

For any inquiry on research and publications, please contact Dr. Chuanzhen Zhao via email.

©2025 by Chuanzhen Zhao. All rights reserved.

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