Our Vision
We develop soft molecular bioelectronic interfaces to monitor, decode, and control chemical signals in living systems. Chronic diseases progress silently at the molecular level, years before symptoms emerge, and the growing burden of an aging population makes this an urgent global challenge. We combine fundamental molecular and materials science with transistor-based bioelectronic design to build platforms that are molecularly specific, electrically programmable, and stable in living systems over clinically relevant timescales.
Our research is organized around three interconnected interfaces:
(1) Bioreceptor Interface: the fundamental surface chemistry, electrochemistry, and molecular physics governing how biomolecular recognition events are transduced with extraordinary sensitivity at the solid-liquid interface of electronic devices
(2) Materials Interface: how soft, tissue-integrated polymer platforms maintain stable biochemical function and mechanical compatibility in living systems over the timescales relevant to chronic disease
(3) Signal Interface: how molecular signals are converted, processed, and used to drive closed-loop therapeutic responses
The CZ Lab is a member of the Acceleration Consortium at the University of Toronto, leveraging AI and self-driving laboratory infrastructure to co-optimize our bioreceptor, materials, and signal interfaces through autonomous experimentation. We are also affiliated with the KITE Research Institute and University Health Network (UHN), one of the world's leading hospital and research systems, connecting our molecular science directly to clinical translation and patient impact.
Our Toolkit
